4,5-Dichlorothiophene-2-carboxylic acid , 98% , 31166-29-7

CAS NO.：31166-29-7

Empirical Formula: C5H2Cl2O2S

Molecular Weight: 197.04

MDL number: MFCD07366674

EINECS: 1312995-182-4

PRODUCT Properties

• Melting point: 196-197 °C
• Boiling point: 315.3±37.0 °C(Predicted)
• Density: 1.708±0.06 g/cm3(Predicted)
• storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• solubility: DMSO, Methanol (Slightly)
• form: Solid
• pka: 3.31±0.10(Predicted)
• color: Pale Beige to Dark Brown
• InChI: InChI=1S/C5H2Cl2O2S/c6-2-1-3(5(8)9)10-4(2)7/h1H,(H,8,9)
• InChIKey: JDBAYLWBVQVMTD-UHFFFAOYSA-N
• SMILES: C1(C(O)=O)SC(Cl)=C(Cl)C=1

Description and Uses

4,5-Dichlorothiophene-2-carboxylic Acid is used in the preparation of compounds that have therapeutic BACE1 and BACE2 inhibitors which are used for the treatment of Alzheimer’s disease, type 2 diabetes and other metabolic disorders.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H317-H319
• Precautionary statements: P280-P305+P351+P338
• Risk Statements: 36/37/38-20/22
• Safety Statements: 20-26-35
• HS Code: 29349990