A3857432
Palbociclib isethionate , 98% , 827022-33-3
Synonym(s):
6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one 2-hydroxy-ethanesulfonic acid (1:1);Palbociclib isethionate
CAS NO.：827022-33-3
Empirical Formula: C26H35N7O6S
Molecular Weight: 573.664
MDL number: MFCD22666589
EINECS: 804-556-2
| Pack Size | Price | Stock | Quantity |
| 25mg | RMB287.20 | In Stock |
|
| 100mg | RMB799.20 | In Stock |
|
| 500MG | RMB2799.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| storage temp. | room temp |
| solubility | ≥28.7 mg/mL in DMSO; insoluble in EtOH; ≥26.8 mg/mL in H2O |
| form | powder |
| color | white to beige |
| Water Solubility | H2O: 5mg/mL, clear |
| InChIKey | LYYVFHRFIJKPOV-UHFFFAOYSA-N |
| SMILES | C(CO)S(O)(=O)=O.O=C1C(=C(C)C2=CN=C(NC3N=CC(N4CCNCC4)=CC=3)N=C2N1C1CCCC1)C(=O)C |
| CAS DataBase Reference | 827022-33-3 |
Description and Uses
PD 0332991 isethionate has been used:
- to incubate MCF10A cells to verify cyclin D1 inhibition of autophagy involved cyclin-dependent kinase activity
- as a cyclin dependent kinase 4 (CDK4) inhibitor to study its anticonvulsive property in Drosophila
- to mimic the inhibitory effect of 5α-dihydrotestosterone (DHT) on HPr-1AR cell cycle progression and growth
