Epirubicin hydrochloride , ≥98%(HPLC) , 56390-09-1

Synonym(s):
4′-Epidoxorubicin hydrochloride;Epidoxorubicin hydrochloride

CAS NO.：56390-09-1

Empirical Formula: C27H30ClNO11

Molecular Weight: 579.98

MDL number: MFCD00274554

EINECS: 260-145-2

PRODUCT Properties

• Melting point: 185°C dec.
• alpha: D20 +274° (c = 0.01 in methanol)
• RTECS: QI9295750
• Flash point: 443.8℃
• storage temp.: Inert atmosphere,Store in freezer, under -20°C
• solubility: Soluble in DMSO to 100mM, or in ethanol to 10mM
• form: powder
• color: red to deep red
• Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
• InChIKey: MWWSFMDVAYGXBV-UAOJCOQHSA-N
• SMILES: C12=C(O)C3=C(C(=O)C4=C(C3=O)C=CC=C4OC)C(O)=C1[C@@]([H])(O[C@H]1O[C@@H](C)[C@H](O)[C@@H](N)C1)C[C@](O)(C(=O)CO)C2.Cl

Description and Uses

Epirubicin hydrochloride is an antitumor antibiotic which is epimeric with doxorubicin a t the 4’-position of the amino sugar moiety. It has shown utility in the treatment of mammary, gastric, colorectal, pulmonary and ovarian carcinomas, as well as malignant lymphoma and melanoma and soft tissue sarcoma. It is reported to be less sardiotoxic than doxorubicin.

Cell-permeable anthracycline anti-tumor antibiotic

Safety

• Symbol(GHS): GHS07,GHS08
• Signal word: Danger
• Hazard statements: H302-H340-H350-H360
• Precautionary statements: P201-P301+P312+P330-P308+P313
• Hazard Codes: Xn
• Risk Statements: 22-63-62-46-40
• Safety Statements: 36/37/38-45-46
• WGK Germany: 3
• HS Code: 29419090