PRODUCT Properties
| Melting point: | 200 °C (dec.)(lit.) |
| alpha | -20.7 º (c=2.5, 0.1N NaOH/H2O) |
| Boiling point: | 546.5°C (rough estimate) |
| Density | 2.405±0.06 g/cm3(Predicted) |
| refractive index | 1.2 ° (C=5, 1mol/L HCl) |
| storage temp. | 2-8°C |
| solubility | Aqueous Acid (Slightly), DMSO (Slightly) |
| pka | 2.12(at 25℃) |
| form | crystalline |
| color | white |
| Water Solubility | slightly soluble |
| Sensitive | Light Sensitive |
| CAS DataBase Reference | 300-39-0(CAS DataBase Reference) |
| NIST Chemistry Reference | 3,5-Diiodo-l-tyrosine(300-39-0) |
| EPA Substance Registry System | L-Tyrosine, 3,5-diiodo- (300-39-0) |
Description and Uses
Diiodotyrosine does not possess pronounced hormonal activity. However, it stops production of thyrotropic hormone by the anterior lobe of the hypophysis, which activates thyroid gland activity.
3,5-Diiodo-L-tyrosine Dihydrate is a thyroid hormone receptor agonist.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-37/39-36/37-24/25 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| F | 8 |
| TSCA | Yes |
| HS Code | 29225090 |
