Home Categories Chemical Reagents 2-Fluoro-3-pyridineboronic acid
A4282412

2-Fluoro-3-pyridineboronic acid , 97% , 174669-73-9

Synonym(s):
(2-Fluoropyridin-3-yl)boronic acid

CAS NO.:174669-73-9

Empirical Formula: C5H5BFNO2

Molecular Weight: 140.91

MDL number: MFCD04038758

Pack Size Price Stock Quantity
1G RMB24.00 In Stock
5G RMB84.80 In Stock
25g RMB286.40 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Melting point: 274-283 °C
Boiling point: 322.6±52.0 °C(Predicted)
Density  1.34±0.1 g/cm3(Predicted)
storage temp.  Inert atmosphere,Store in freezer, under -20°C
solubility  soluble in Methanol
form  solid
pka 6.68±0.58(Predicted)
color  white
BRN  9119935
InChI 1S/C5H5BFNO2/c7-5-4(6(9)10)2-1-3-8-5/h1-3,9-10H
InChIKey YUHZIUAREWNXJT-UHFFFAOYSA-N
SMILES OB(O)c1cccnc1F
CAS DataBase Reference 174669-73-9(CAS DataBase Reference)

Description and Uses

Reactant involved in:

  • Heterocyclization eith α-oxocarboxylic acids
  • Suzuki-Miyaura coupling reactions

Additionally used as a precursor to biologically active molecules including:
  • Heteroaryl benzylureas with glycogen synthase kinase 3 inhibitory activity
  • Carboxyindoles with HCV NS5B polymerase inhibitory activity
  • Pyrazolyl- and thienyl-aminohydantoins with BACE1 inhibitory activity

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338-P280a-P304+P340-P405-P501a
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
TSCA  No
HazardClass  IRRITANT
HS Code  29333990
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

RELATED PRODUCTS