Ferrocenecarboxylic acid , 98% , 1271-42-7

Synonym(s):
Cyclopentadienecarboxylic acid;Ferrocenemonocarboxylic acid;Carboxyferrocene;Carboxylferrocene;(Carboxycyclopentadienyl)cyclopentadienyliron

CAS NO.：1271-42-7

Empirical Formula: C11H10FeO210*

Molecular Weight: 230.04

MDL number: MFCD00001430

EINECS: 215-040-6

PRODUCT Properties

• Melting point: 210 °C (dec.)(lit.)
• storage temp.: Inert atmosphere,Room Temperature
• solubility: Chloroform (Sparingly), DMSO (Slightly), Methanol (Slightly)
• form: crystal
• color: yellow
• Water Solubility: Insoluble in water.
• Exposure limits: ACGIH: TWA 1 mg/m3; NIOSH: TWA 1 mg/m3
• Stability: Stable. Incompatible with strong oxidizing agents.
• InChI: InChI=1S/C6H5O2.C5H5.Fe/c7-6(8)5-3-1-2-4-5;1-2-4-5-3-1;/h1-4H,(H,7,8);1-5H
• InChIKey: VUJLGCHOGQEAED-UHFFFAOYSA-N
• SMILES: [C]1(C(=O)O)[CH][CH][CH][CH]1.[CH]1[CH][CH][CH][CH]1.[Fe] |^1:0,4,5,6,7,8,9,10,11,12|
• CAS DataBase Reference: 1271-42-7(CAS DataBase Reference)
• NIST Chemistry Reference: Ferrocene carboxylic acid(1271-42-7)

Description and Uses

Ferrocenecarboxylic acid is a metal-organic compound characterized by connecting two ferrocene molecules through a carboxy ligand. Notably, ferrocene is a stable yet highly reactive metal-organic compound that has been extensively researched due to its potential applications in catalysis, materials science, and medicine. It serves as a catalyst in catalysis, facilitating the synthesis of diverse compounds through polymerization, oxidation, and reduction reactions. In materials science, it acts as a fundamental molecular building block for synthesizing polymers and nanomaterials. Although the precise mechanism of action of Ferrocenecarboxylic acid remains fully elucidated, it is believed that the carboxy ligand binds to the ferrocene molecules, forming a stable complex. This complex, in turn, engages with other molecules, including proteins, to facilitate various reactions[1-2].

Ferrocenecarboxylic acid (FCA) is a multifunctional organic reagent with applications in the following areas:
(1) As a synthetic precursor: synthesising amino-MIL-53(Al) through the adsorption of ferrocene and FCA. Amino-MIL-53(Al) is an amino-functionalised derivative of the metal-organic framework MIL-53(Al).
(2) As a chemical additive: Employed in preparing electrode materials and for the electrocatalytic oxidation of NADH.
(3) Based on Fca, ferrocenecarboxylic acid-capped pillar[5]arene (FACP5) was synthesised as a guest molecule. This interacts with the host molecule, a galactose derivative (G), to form a supramolecular vesicle system suitable for targeted drug delivery.
(4) Fca serves as the key substance generating electrical signals in electrochemical sensors for prostate-specific antigen (PSA) detection. This sensor is suitable for the early clinical diagnosis of prostate cancer.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P280g-P305+P351+P338
• PPE: Eyeshields, Gloves, type N95 (US)
• Hazard Codes: Xn
• Risk Statements: 36/37/38-22
• Safety Statements: 37/39-26
• WGK Germany: 3
• HS Code: 29319090
• Storage Class: 11 - Combustible Solids