Fmoc N-hydroxysuccinimide ester , 98% , 82911-69-1
Synonym(s):
N-(9-Fluorenylmethoxycarbonyloxy)succinimide;9-Fluorenylmethyl N-succinimidyl carbonate;FMOC-ONSu, N-(9H-Fluoren-9-ylmethoxycarbonyloxy)succinimide;Fmoc-OSu;N-(9-Fluorenylmethoxycarbonyloxy)succinimide, 9-Fluorenylmethyl-succinimidyl carbonate
CAS NO.：82911-69-1
Empirical Formula: C19H15NO5
Molecular Weight: 337.33
MDL number: MFCD00010733
EINECS: 433-520-5
| Pack Size | Price | Stock | Quantity |
| 5G | RMB23.20 | In Stock |
|
| 25G | RMB31.20 | In Stock |
|
| 100G | RMB116.00 | In Stock |
|
| 500G | RMB508.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 150-153 °C(lit.) |
| Boiling point: | 150-153°C |
| Density | 1.3460 (rough estimate) |
| refractive index | 1.5000 (estimate) |
| storage temp. | 2-8°C |
| solubility | Soluble in dimethyl sulfoxide and dimethyl formamide. |
| form | Microfine Powder |
| color | White or almost white |
| Sensitive | Moisture Sensitive |
| BRN | 3569540 |
| Stability: | Moisture Sensitive |
| InChI | InChI=1S/C19H15NO5/c21-17-9-10-18(22)20(17)25-19(23)24-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16H,9-11H2 |
| InChIKey | WMSUFWLPZLCIHP-UHFFFAOYSA-N |
| SMILES | C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)(=O)ON1C(=O)CCC1=O |
| CAS DataBase Reference | 82911-69-1(CAS DataBase Reference) |
Description and Uses
Fmoc-OSu (N-(9-Fluorenylmethoxycarbonyloxy)succinimide) is a reagent used in solid-phase peptide synthesis (SPPS) for Fmoc protection of amino groups, particularly amino acids. This reagent contains an Fmoc functional group, which is stable under acidic conditions and cleaves under alkaline conditions. Fmoc-OSu reacts with amino groups to form stable amide bonds, helping to reduce the occurrence of side reactions. Additionally, Fmoc-OSu can also be used as a fluorescent reagent.
N-(9-Fluorenylmethoxycarbonyloxy)succinimide is used in conjunction with Isothiocyanate to conduct partial Edman Degradation on biologically active peptides.
Safety
| Symbol(GHS) |   GHS07,GHS09 |
| Signal word | Warning |
| Hazard statements | H302-H317-H411 |
| Precautionary statements | P261-P264-P273-P280-P301+P312-P302+P352 |
| Hazard Codes | Xi,N,Xn |
| Risk Statements | 36/37/38-51/53-43-22 |
| Safety Statements | 22-24/25-26/37/39-26-61-37-24 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | 3 |
| F | 10-21 |
| Hazard Note | Moisture Sensitive |
| HazardClass | 9 |
| HS Code | 29251995 |
