Fmoc-Thr(tBu)-OH , 98% , 71989-35-0

Synonym(s):
Fmoc-O-tert-butyl-L-threonine;Fmoc-Thr(tBu)-OH;N-α-Fmoc-O-t.-butyl-L-threonine

CAS NO.：71989-35-0

Empirical Formula: C23H27NO5

Molecular Weight: 397.46

MDL number: MFCD00077075

EINECS: 276-261-1

PRODUCT Properties

• Melting point: 131-134 °C
• alpha: 40 º (c=1, chloroform)
• Boiling point: 520.91°C (rough estimate)
• Density: 1.2197 (rough estimate)
• refractive index: 15 ° (C=1, AcOEt)
• storage temp.: 2-8°C
• solubility: almost transparency in Ethylacetate
• pka: 3.42±0.10(Predicted)
• form: Fine Fluffy Crystalline Powder
• color: White
• optical activity: [α]20/D +16±1°, c = 1% in ethyl acetate
• BRN: 4581133
• InChIKey: LZOLWEQBVPVDPR-VLIAUNLRSA-N
• SMILES: C(O)(=O)[C@H]([C@H](OC(C)(C)C)C)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
• CAS DataBase Reference: 71989-35-0(CAS DataBase Reference)

Description and Uses

Fmoc-Thr(tBu)-OH can be used to synthesize chlorofusin analogues via solid phase peptide synthesis. Additionally, it can serve as a protecting group for both the amine and the hydroxyl functions in solid-phase synthesis of complex depsipeptides.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P280a-P304+P340-P305+P351+P338-P405-P501a
• Hazard Codes: Xi,N
• Risk Statements: 36/37/38-50/53
• Safety Statements: 24/25-36/37/39-27-26-61-60-29/56
• RIDADR: 3077
• WGK Germany: 3
• HS Code: 29242990