Fmoc-Lys-OH·HCl , 98% , 139262-23-0

Synonym(s):
N_α-Fmoc-L-lysine hydrochloride

CAS NO.：139262-23-0

Empirical Formula: C21H25ClN2O4

Molecular Weight: 404.89

MDL number: MFCD00190889

PRODUCT Properties

• refractive index: -11.0 ° (C=1, DMF)
• storage temp.: 2-8°C
• solubility: Soluble in dimethyl formamide (0.3g in 2ml).
• form: powder to crystal
• color: White to Almost white
• BRN: 8663370
• InChIKey: MVMZFAIUUXYFGY-FYZYNONXSA-N
• SMILES: C(C1C2=CC=CC=C2C2C=CC=CC1=2)OC(=O)N[C@H](C(=O)O)CCCCN.Cl |&1:18,r|
• CAS DataBase Reference: 139262-23-0(CAS DataBase Reference)

Description and Uses

Fmoc-Lys-OH hydrochloride is a cleavable ADC linker used to synthesize antibody-drug conjugates (ADCs). Fmoc-Lys-OH hydrochloride is also an alkyl chain-based PROTAC linker that can be used to synthesize PROTACs.

Fmoc-Lys-OH hydrochloride is used as an active pharmaceutical intermediate and in the synthesis of nε-(7-diethylaminocoumarin-3-carboxyl)- and nε-(7-methoxycoumarin-3-carboxyl)-l-fmoc lysine as tools for protease cleavage detection by fluorescence.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• Safety Statements: 24/25
• WGK Germany: 3
• HS Code: 29242990