Fmoc-D-Leu-OH , 98% , 114360-54-2

Synonym(s):
Fmoc-D-leucine;Fmoc-D-Leu-OH;N-α-Fmoc-D-leucine

CAS NO.：114360-54-2

Empirical Formula: C21H23NO4

Molecular Weight: 353.41

MDL number: MFCD00062957

EINECS: 252-662-7

PRODUCT Properties

• Melting point: 155°C
• Boiling point: 559.8±33.0 °C(Predicted)
• Density: 1?+-.0.06 g/cm3(Predicted)
• refractive index: 25 ° (C=1, DMF)
• storage temp.: 2-8°C
• solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
• form: powder to crystal
• pka: 3.91±0.21(Predicted)
• color: White to Almost white
• optical activity: Consistent with structure
• Water Solubility: Insoluble in water.
• InChI: InChI=1S/C21H23NO4/c1-13(2)11-19(20(23)24)22-21(25)26-12-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h3-10,13,18-19H,11-12H2,1-2H3,(H,22,25)(H,23,24)/t19-/m1/s1
• InChIKey: CBPJQFCAFFNICX-LJQANCHMSA-N
• SMILES: C(O)(=O)[C@@H](CC(C)C)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
• CAS DataBase Reference: 114360-54-2(CAS DataBase Reference)

Description and Uses

A convergent synthesis of the proposed structure of (+)-pestalazine B has been achieved in 4 steps using the N-alkylation of an unprotected tryptophan diketopiperazine with a 3a-bromopyrrolidinoindoline where the condensation between L-tryptophan methyl ester and N-Fmoc-D-leucine in the presence of EDC as coupling agent afforded the corresponding L-Trp-D-Leu dipeptide.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335-H413
• Precautionary statements: P261-P305+P351+P338
• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 10
• HS Code: 29224999