Fmoc-D-Ser-OH , 98% , 116861-26-8

Synonym(s):
Fmoc-D-Ser-OH;N-α-Fmoc-D-serine

CAS NO.：116861-26-8

Empirical Formula: C18H17NO5

Molecular Weight: 327.33

MDL number: MFCD00077068

EINECS: 1533716-785-6

PRODUCT Properties

• Melting point: 108-112 °C
• Boiling point: 599.3±50.0 °C(Predicted)
• Density: 1.362±0.06 g/cm3(Predicted)
• refractive index: 11.0 ° (C=1, DMF)
• storage temp.: Sealed in dry,2-8°C
• solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
• pka: 3.51±0.10(Predicted)
• form: powder to crystal
• color: White to Light yellow
• Major Application: peptide synthesis
• InChI: 1S/C18H17NO5/c20-9-16(17(21)22)19-18(23)24-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15-16,20H,9-10H2,(H,19,23)(H,21,22)/t16-/m1/s1
• InChIKey: JZTKZVJMSCONAK-MRXNPFEDSA-N
• SMILES: N([C@H](CO)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3
• CAS DataBase Reference: 116861-26-8(CAS DataBase Reference)

Description and Uses

N-Fmoc-D-serine is an N-Fmoc-protected form of D-Serine (S270975). D-Serine is a neurotransmitter that is concentrated in the mammalian brain, and is one of the very few amino acids that occur in the D- and L-configurations in significant amounts. D-Serine is an potent agonist of the N-methyl-D-aspartate (NMDA) receptor in the brain, which is associated with schizophrenia. Use of D-Serine has been considered as an additional therapy for refractory schizophrenic patients.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 10
• HS Code: 29242990
• Storage Class: 11 - Combustible Solids