Fluocinolone Acetonide , ≥98% , 67-73-2

Synonym(s):
Fluocinolone acetonide;Sinalar;Synandone;6α,9α-Difluoro-11β,16α,17α,21-tetrahydroxy-1,4-pregnadiene-3,20-dione;6α,9α-Difluoro-16α-hydroxyprednisolone 16,17-acetonide

CAS NO.：67-73-2

Empirical Formula: C24H30F2O6

Molecular Weight: 452.49

MDL number: MFCD00010525

EINECS: 200-668-5

PRODUCT Properties

• Melting point: 267-269 °C(lit.)
• alpha: D +95° (chloroform)
• Boiling point: 578.5±50.0 °C(Predicted)
• Density: 1.1826 (estimate)
• refractive index: 103 ° (C=1, MeOH)
• storage temp.: Refrigerator
• solubility: Practically insoluble in water, soluble in acetone and in ethanol
• pka: 12.78±0.70(Predicted)
• form: Solid
• color: White to Off-White
• Water Solubility: Soluble in water (partly), DMSO, alcohol, chloroform and methanol.
• Merck: 14,4150
• Major Application: forensics and toxicology; veterinary
• InChIKey: FEBLZLNTKCEFIT-VSXGLTOVSA-N
• SMILES: CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
• CAS DataBase Reference: 67-73-2(CAS DataBase Reference)
• EPA Substance Registry System: Fluocinolone acetonide (67-73-2)

Description and Uses

A synthetic glucocorticoid VEGF inhibitor; anti-inflammatory.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• target organs: Respiratory system
• PPE: dust mask type N95 (US), Eyeshields, Gloves
• Hazard Codes: Xi,Xn
• Risk Statements: 36/37/38-40-20/21/22
• Safety Statements: 26-36-22
• WGK Germany: 3
• RTECS: TU3830000
• HS Code: 2937220000
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Eye Irrit. 2; Skin Irrit. 2; STOT SE 3
• Hazardous Substances Data: 67-73-2(Hazardous Substances Data)
• Toxicity: LD50 oral in rat: > 4gm/kg