Fluocinonide , 98% , 356-12-7

Synonym(s):
(6α,11β,16α)-21-(acetyloxy)-6,9-difluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione;Fluocinonide;Lonide

CAS NO.：356-12-7

Empirical Formula: C26H32F2O7

Molecular Weight: 494.52

MDL number: MFCD00079302

EINECS: 206-597-6

PRODUCT Properties

• Melting point: 309 °C
• alpha: D +83° (chloroform)
• Boiling point: 235°C (rough estimate)
• Density: 1.2001 (estimate)
• storage temp.: 2-8°C
• solubility: DMSO: ≥19mg/mL
• pka: 12.77±0.70(Predicted)
• form: powder
• color: white to tan
• optical activity: [α]/D +75 to +90°, c = 1 in dichloromethane
• Water Solubility: 0.53mg/L(25 ºC)
• InChIKey: WJOHZNCJWYWUJD-IUGZLZTKSA-N
• SMILES: [C@@]12(C(=O)COC(=O)C)OC(C)(C)O[C@@H]1C[C@@]1([H])[C@]3([H])C[C@@H](C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]21C)F |&1:0,13,15,17,20,27,29,31,34,r|

Description and Uses

Glucocorticoid; anti-inflammatory.

Safety

• Symbol(GHS): GHS06,GHS08
• Signal word: Danger
• Hazard statements: H300-H361
• Precautionary statements: P201-P301+P310+P330
• Hazard Codes: T+
• Risk Statements: 28-63
• Safety Statements: 22-25-28-36/37/39-45
• RIDADR: UN 2811 6.1/PG 2
• WGK Germany: 3
• RTECS: TU3831000
• HazardClass: 6.1(a)
• PackingGroup: I
• HS Code: 2937220000
• Toxicity: guinea pig,LD50,subcutaneous,> 3170mg/kg (3170mg/kg),Drugs in Japan Vol. 6, Pg. 694, 1982.