Grubbs Catalyst, 2nd Generation , 246047-72-3

Synonym(s):
(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium;Benzylidene[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(tricyclohexylphosphine)ruthenium;Dichloro[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene](benzylidene)(tricyclohexylphosphine)ruthenium(II);Grubbs Catalyst 2nd Generation;Grubbs Catalyst M2a (C848)

CAS NO.：246047-72-3

Empirical Formula: C46H65Cl2N2PRu

Molecular Weight: 848.98

MDL number: MFCD03453237

EINECS: 688-322-3

PRODUCT Properties

• Melting point: 143.5-148.5 °C(lit.)
• storage temp.: 2-8°C
• solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Very Slightly, Heated)
• form: Solid
• color: Brown to Very Dark Brown to Very Dark Red
• InChIKey: FCDPQMAOJARMTG-UHFFFAOYSA-L
• SMILES: P(C1CCCCC1)(C1CCCCC1)(C1CCCCC1)[Ru+6](=[C-2]1N(C2C(=CC(C)=CC=2C)C)CCN1C1C(=CC(C)=CC=1C)C)([Cl-])([Cl-])=[C-2]C1C=CC=CC=1
• EPA Substance Registry System: Ruthenium, [1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)- (246047-72-3)

Description and Uses

Grubbs Catalyst^? M204 can be used as a catalyst for ring-closing metathesis (RCM), cross-metathesis, and ring-opening metathesis polymerization (ROMP). It is also used to synthesize trisubstituted olefins with excellent functional group tolerance and selectivity via cross-metathesis and ring closing metathesis reactions.
It can also be used as a catalyst:

• To synthesize coumarins from phenolic compounds via RCM.
• To cleave secondary (E)-allyl vic-diols to aldehydes.

Safety

• Symbol(GHS): GHS02
• Signal word: Warning
• Hazard statements: H228
• Precautionary statements: P210-P240-P241-P280-P370+P378
• Hazard Codes: F
• Risk Statements: 36/37/38-11
• Safety Statements: 26-36/37/39
• RIDADR: 1325
• WGK Germany: 3
• F: 10-23
• HazardClass: 4.1
• PackingGroup: Ⅱ