Hydroxyecdysone , ≥95%(HPLC), powder , 5289-74-7

Synonym(s):
β-Ecdysone;2β,3β,14α,20β,22,25-Hexahydroxy-7-cholesten-6-one;Ecdysterone;Insect moulting hormone;Polypodine A

CAS NO.：5289-74-7

Empirical Formula: C27H44O7

Molecular Weight: 480.64

MDL number: MFCD00036740

EINECS: 811-097-1

PRODUCT Properties

• Melting point: 242-244 °C
• Boiling point: 498.63°C (rough estimate)
• Density: 1.0760 (rough estimate)
• refractive index: 1.5800 (estimate)
• storage temp.: Sealed in dry,Store in freezer, under -20°C
• solubility: alcohol: soluble
• form: powder
• pka: 14.13±0.70(Predicted)
• color: white
• Merck: 13,3525
• BRN: 1917578
• InChIKey: NKDFYOWSKOHCCO-YPVLXUMRSA-N
• SMILES: O[C@@]12CC[C@]([H])([C@](O)(C)[C@H](O)CCC(O)(C)C)[C@]1(CC[C@]1([H])[C@]3(C[C@H](O)[C@H](O)C[C@@]3([H])C(=O)C=C21)C)C |&1:1,4,6,9,17,20,22,24,26,29,r|
• LogP: -0.270 (est)
• CAS DataBase Reference: 5289-74-7(CAS DataBase Reference)

Description and Uses

20-Hydroxyecdysone (also known as Ecdysterone) is a hormone-like substance widely found in animals and plants, with a steroid ring at the core of its structure. It has the function of promoting arthropod molting and protecting plants from insects. Studies have shown that when used as a supplement, ecdysterone has a positive effect on human measurements and performance parameters, and is included in the World Anti-Doping Agency's banned list, but it has recently been found that there is a lack of scientific evidence to support WADA's ban on this substance.

20-Hydroxyecdysone has been used:
in Leibovitz′s dissecting medium for culturing sorting zone and neuropil-associated glia and antennal lobes of Manduca sexta
in Schneider′s medium to reproduce ex-vivo imaginal disc eversion
as a supplement in Mcl8 medium for culturing Drosophila wing imaginal discs
as an insect molting hormone

Safety

• Symbol(GHS): GHS09
• Signal word: Warning
• Hazard statements: H410
• Precautionary statements: P501-P273-P391
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 22-24/25-36-26
• WGK Germany: 2
• RTECS: FZ8060000
• F: 10
• HS Code: 29372900