Hygromycin B , Powder, ≥60%(HPLC) , 31282-04-9
Synonym(s):
Hygromycin;Hygromycin B from Streptomyces hygroscopicus;Hygromycin B, Streptomyces sp. - CAS 31282-04-9 - Calbiochem;Hygromycin B, Streptomyces sp., Cell Culture-Tested - CAS 31282-04-9 - Calbiochem;Hygromycin B, Streptomyces sp., Sterile-Filtered Solution in 25 mM HEPES, Cell Culture-Tested - CAS 31282-04-9 - Calbiochem
CAS NO.：31282-04-9
Empirical Formula: C20H37N3O13
Molecular Weight: 527.52
MDL number: MFCD06795480
EINECS: 250-545-5
| Pack Size | Price | Stock | Quantity |
| 50MG | RMB111.20 | In Stock |
|
| 250MG | RMB207.20 | In Stock |
|
| 200mg | RMB392.00 | In Stock |
|
| 1G | RMB639.20 | In Stock |
|
| 5G | RMB2239.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 160-180°C |
| alpha | D20 +20.2° (c = 1 in water) |
| Boiling point: | 608.13°C (rough estimate) |
| Density | 1.4252 (rough estimate) |
| refractive index | 1.6300 (estimate) |
| storage temp. | 2-8°C |
| solubility | H2O: 50 mg/mL As a stock solution. Stock solutions should be stored at 2-8°C. Stable at 37°C for 30 days. |
| form | powder |
| pka | 7.1, 8.8(at 25℃) |
| color | faintly brown to brown |
| PH | pH (25g/l, 25℃ ) : 9.5～12.5 |
| biological source | Streptomyces hygroscopicus |
| Water Solubility | Miscible with water, methanol, buffer solution and ethanol. Immiscible with less polar solvents. |
| Merck | 14,4852 |
| BRN | 6755837 |
| Stability: | Hygroscopic |
| InChIKey | GRRNUXAQVGOGFE-KPBUCVLVSA-N |
| EPA Substance Registry System | Hygromycin B (31282-04-9) |
Description and Uses
Hygromycin B is an aminoglycoside antibiotic that has been found in S. hygroscopicus. It is active against E. coli (MIC = 150 μg/ml) and cytotoxic to both prokaryotic and eukaryotic cells via inhibition of protein synthesis. Hygromycin B has commonly been used in molecular and cell biology applications to select for transformed cells expressing the E. coli hygromycin resistance genes hyg or hph.
Hygromycin B, a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H300+H330 |
| Precautionary statements | P260-P264-P270-P271-P284-P304+P340+P310 |
| Hazard Codes | T+,Xn,T |
| Risk Statements | 26/27/28-41-42/43-40-36-23/24/25 |
| Safety Statements | 23-26-28-36/37/39-45-22-36-36/37 |
| RIDADR | UN 3462 6.1/PG 1 |
| WGK Germany | 3 |
| RTECS | WK2130000 |
| F | 19 |
| HazardClass | 6.1 |
| PackingGroup | I |
| HS Code | 29419059 |
| Storage Class | 6.1B - Non-combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
| Hazard Classifications | Acute Tox. 1 Inhalation Acute Tox. 3 Oral Acute Tox. 4 Dermal |
| Toxicity | mmo-esc 250 mg/L AACHAX 18,798,80 |
