Calcifediol monohydrate , 98% , 63283-36-3

Synonym(s):
25-Hydroxycholecalciferol;25-Hydroxyvitamin D₃ monohydrate

CAS NO.：63283-36-3

Empirical Formula: C27H46O3

Molecular Weight: 418.66

MDL number: MFCD00867077

EINECS: 621-370-5

PRODUCT Properties

• Flash point: 14℃
• storage temp.: -20°C
• solubility: Practically insoluble in water, freely soluble in ethanol (96 per cent), soluble in fatty oils.
• form: Solid
• color: White to Light yellow
• biological source: synthetic
• BRN: 4270041
• InChIKey: JWUBBDSIWDLEOM-LCDSLSDMSA-N
• SMILES: C[C@]12CCC/C(=C\C=C3\C[C@@H](O)CCC\3=C)/[C@]1([H])CC[C@]2([H])[C@H](C)CCCC(O)(C)C.O |&1:1,10,16,20,22,r|
• CAS DataBase Reference: 63283-36-3(CAS DataBase Reference)

Description and Uses

Calcifediol monohydrate (25-hydroxyvitamin D3 monohydrate) is a potent VDR ligand and vitamin D supplement. Calcifediol is a precursor of the Vitamin D Endocrine System (VDES), which is hydroxylated in the liver to produce the active form of calcitriol. Calcifediol rapidly raises serum levels of Calcifediol rapidly increases serum levels of vitamin D.

Calcifediol is a major circulating metabolite of vitamin D3 and acts as a competitive inhibitor with an apparent Ki of 3.9 μM. It is produced in the liver and is the best indicator of the body’s vitamin D stores. It is effective in the treatment of ricket

Safety

• Symbol(GHS): GHS06,GHS08
• Signal word: Danger
• Hazard statements: H300+H310+H330-H372
• Precautionary statements: P260-P262-P280-P301+P330+P331+P310-P302+P352+P310-P304+P340+P310
• Hazard Codes: T+
• Risk Statements: 28-48/25-26-24/25
• Safety Statements: 28-36/37-45
• RIDADR: UN 2811 6.1/PG 2
• WGK Germany: 3
• F: 8-10-19
• HS Code: 29362900