3-Hydroxyoxetane , 95% , 7748-36-9

Synonym(s):
1,3-Epoxy-2-propanol;3-Oxetanol

CAS NO.：7748-36-9

Empirical Formula: C3H6O2

Molecular Weight: 74.08

MDL number: MFCD09056790

EINECS: 663-648-9

PRODUCT Properties

• Boiling point: 153℃
• Density: 1.167
• refractive index: 1.438
• Flash point: 87°(189°F)
• storage temp.: Inert atmosphere,2-8°C
• solubility: Chloroform (Soluble), Methanol (Slightly)
• form: Liquid
• pka: 13.68±0.20(Predicted)
• color: Clear colorless
• InChI: InChI=1S/C3H6O2/c4-3-1-5-2-3/h3-4H,1-2H2
• InChIKey: QMLWSAXEQSBAAQ-UHFFFAOYSA-N
• SMILES: O1CC(O)C1

Description and Uses

3-Oxetanol is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.

Safety

• Symbol(GHS): GHS05,GHS07
• Signal word: Danger
• Hazard statements: H302-H315-H318-H335
• Precautionary statements: P261-P264-P280-P301+P312-P302+P352-P305+P351+P338
• Hazard Codes: Xn
• Risk Statements: 22-37/38-41
• Safety Statements: 26-39
• RIDADR: NA 1993 / PGIII
• WGK Germany: 3
• TSCA: No
• HS Code: 29329990