Home Categories Biochemical Engineering 2'-Deoxy-7,8-dihydro-8-oxoguanosine
A4784812

2'-Deoxy-7,8-dihydro-8-oxoguanosine , ≥95.0%(HPLC) , 88847-89-6

Synonym(s):
8-Oxo-7,8-dihydro-2′-deoxyguanosine;8-Oxo-dG

CAS NO.:88847-89-6

Empirical Formula: C10H13N5O5

Molecular Weight: 283.24

MDL number: MFCD00210311

Pack Size Price Stock Quantity
1MG RMB319.20 In Stock
5MG RMB1119.20 In Stock
25mg RMB3199.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 217-220°C
Density  2.25±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  Soluble in DMSO (up to 10 mg/ml).
pka 7.86±0.20(Predicted)
form  White to off-white solid.
color  Off-white
Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
InChI InChI=1S/C10H13N5O5/c11-9-13-7-6(8(18)14-9)12-10(19)15(7)5-1-3(17)4(2-16)20-5/h3-5,16-17H,1-2H2,(H,12,19)(H3,11,13,14,18)/t3-,4+,5+/m0/s1
InChIKey HCAJQHYUCKICQH-VPENINKCSA-N
SMILES OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)N)=O)NC2=O)C[C@@H]1O

Description and Uses

8-Oxo-2′-deoxyguanosine (88847-89-6) is a useful marker for DNA damage via a variety of oxidative processes.1It is a critical biomarker for oxidative stress and carcinogenesis.2,3

A marker compound indicative of DNA damage associated with mutagenesis and carcinogenesis. Can induce differentiation of Friend murine erythroleukemia cells in vitro.

Safety

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
PPE Eyeshields, Gloves, type N95 (US)
Safety Statements  24/25
WGK Germany  3
RTECS  MF8782675
HS Code  29349990
Storage Class 11 - Combustible Solids

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