5-Hydroxy-2-methylpyridine , >98.0%(T) , 1121-78-4

Synonym(s):
6-Methyl-3-pyridinol

CAS NO.：1121-78-4

Empirical Formula: C6H7NO

Molecular Weight: 109.13

MDL number: MFCD00006339

EINECS: 214-337-8

PRODUCT Properties

• Melting point: 168-170 °C(lit.)
• Boiling point: 204.59°C (rough estimate)
• Density: 1.1143 (rough estimate)
• refractive index: 1.5040 (estimate)
• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• solubility: dichloromethane: soluble
• pka: 9.49±0.10(Predicted)
• form: Crystalline Powder
• color: Beige to light tan
• BRN: 107077
• InChI: InChI=1S/C6H7NO/c1-5-2-3-6(8)4-7-5/h2-4,8H,1H3
• InChIKey: DHLUJPLHLZJUBW-UHFFFAOYSA-N
• SMILES: C1=NC(C)=CC=C1O
• LogP: 0.418 (est)
• CAS DataBase Reference: 1121-78-4(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinol, 6-methyl-(1121-78-4)

Description and Uses

• 5-Hydroxy-2-methylpyridine was used as starting reagent for the synthesis of 5-[(4-methoxybenzyl)oxy]-2-pyridinecarbaldehyde.
• It was used in synthesis of [HNC₆H₆OH]₂[Cu(NC₅H₅)₄(NbOF₅)₂].
• It was used as ligand of a platinum complex which showed protein kinase inhibitory action at nanomolar levels.
• It forms a chiral pyridinium ionic liquid on reaction with L-menthol chloromethyl ether.

Safety

• Symbol(GHS): GHS05,GHS07
• Signal word: Danger
• Hazard statements: H302-H315-H318-H335
• Precautionary statements: P280-P301+P312+P330-P302+P352-P305+P351+P338+P310
• Hazard Codes: Xn,Xi
• Risk Statements: 22-37/38-41-40-36/37/38
• Safety Statements: 26-39-24/25-36-22
• WGK Germany: 3
• RTECS: UU7714900
• HS Code: 29333990
• Toxicity: mouse,LD50,intraperitoneal,846mg/kg (846mg/kg),Toxicon. Vol. 23, Pg. 815, 1985.