7-<WBR>Hydroxy-<WBR>5-<WBR>methyl[1,2,4]<WBR>triazolo[1,5-<I>a</I>]pyrimidine , 98% , 2503-56-2

Synonym(s):
5-Methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-ol;6-Methyl-4-hydroxy-1,3,3a,7-tetraazaindene;7-Hydroxy-5-methyl-1,3,4-triazaindolizine;NSC 32071;NSC 511493

CAS NO.：2503-56-2

Empirical Formula: C6H6N4O

Molecular Weight: 150.14

MDL number: MFCD00005555

EINECS: 219-706-7

PRODUCT Properties

• Melting point: 280-283 °C(lit.)
• Boiling point: 271.66°C (rough estimate)
• Density: 1.3471 (rough estimate)
• vapor pressure: 0-0Pa at 20-25℃
• refractive index: 1.6700 (estimate)
• storage temp.: 2-8°C
• pka: 1.14±0.53(Predicted)
• form: solid
• color: White to Almost white
• Water Solubility: INSOLUBLE IN COLD WATER
• BRN: 609440
• InChI: 1S/C6H6N4O/c1-4-2-5(11)10-6(9-4)7-3-8-10/h2-3,11H,1H3
• InChIKey: ZUIVNYGZFPOXFW-UHFFFAOYSA-N
• SMILES: Cc1cc(O)n2ncnc2n1
• LogP: -1.4 at 19℃ and pH7.1
• CAS DataBase Reference: 2503-56-2(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrimidin-7-ol, 5-methyl-s-triazolo-[1,5-a]-(2503-56-2)
• EPA Substance Registry System: [1,2,4]Triazolo[1,5-a]pyrimidin-7-ol, 5-methyl- (2503-56-2)

Description and Uses

Reactant for the synthesis of: • ;Ruthenium(II)-Hmtpo complexes1• ;Dihydroorotate dehydrogenase inhibitors with antimalarial activity2Reactant for the Vilsmeier reaction of conjugated carbocycles and heterocycles3Investigations of the pharmacological activity caused by binding to HIV TAR RNA4Additive to study the space charge layer in silver bromide microcrystals5

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P305+P351+P338
• target organs: Respiratory system
• PPE: dust mask type N95 (US), Eyeshields, Gloves
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36-37/39
• WGK Germany: 1
• RTECS: XZ6133300
• F: 9
• Hazard Note: Harmful
• TSCA: TSCA listed
• HS Code: 2933998090
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Eye Irrit. 2; Skin Irrit. 2; STOT SE 3
• Toxicity: mouse,LD50,intravenous,> 450mg/kg (450mg/kg),Oyo Yakuri. Pharmacometrics. Vol. 13, Pg. 597, 1977.
• REACH Registrations: Active