1H-pyrrolo[2,3-b]pyridin-5-ol , 97% , 98549-88-3

CAS NO.：98549-88-3

Empirical Formula: C7H6N2O

Molecular Weight: 134.14

MDL number: MFCD08272242

PRODUCT Properties

• Melting point: 219-220°C
• Boiling point: 381.8±42.0 °C(Predicted)
• Density: 1.41±0.1 g/cm3(Predicted)
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• form: Powder
• pka: 6.93±0.20(Predicted)
• Appearance: Light brown to light yellow Solid
• InChI: InChI=1S/C7H6N2O/c10-6-3-5-1-2-8-7(5)9-4-6/h1-4,10H,(H,8,9)
• InChIKey: VUQZKLXKFUBWRP-UHFFFAOYSA-N
• SMILES: C12NC=CC1=CC(O)=CN=2

Description and Uses

1H-?Pyrrolo[2,?3-?b]?pyridin-?5-?ol is a reagent used in the synthesis of potent VEGFR-2 inhibitors. 7-Azaindole derivative identified as an intermediate in the synthesis of Venetoclax (A112430), a potent and selective BCL-2 inhibitor that achieves potent antitumour activity while sparing platelets.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P280-P305+P351+P338
• Hazard Codes: Xi,Xn
• Risk Statements: 22
• Safety Statements: 24/25
• WGK Germany: 3
• HazardClass: IRRITANT
• HS Code: 29339900