Indole-4-carboxaldehyde , 98% , 1074-86-8

Synonym(s):
4-Formylindole;NSC 337264

CAS NO.：1074-86-8

Empirical Formula: C9H7NO

Molecular Weight: 145.16

MDL number: MFCD01632221

EINECS: 625-162-5

PRODUCT Properties

• Melting point: 139-143 °C(lit.)
• Boiling point: 339.1±15.0 °C(Predicted)
• Density: 1.278±0.06 g/cm3(Predicted)
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: DMF: 10 mg/ml; DMSO: 3 mg/ml; Ethanol: 10 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
• form: powder to crystal
• pka: 15.84±0.30(Predicted)
• color: Light yellow to Brown
• Water Solubility: Soluble in ethanol and acetone. Insoluble in water.
• Sensitive: Air Sensitive
• InChI: InChI=1S/C9H7NO/c11-6-7-2-1-3-9-8(7)4-5-10-9/h1-6,10H
• InChIKey: JFDDFGLNZWNJTK-UHFFFAOYSA-N
• SMILES: N1C2=C(C(C=O)=CC=C2)C=C1
• CAS DataBase Reference: 1074-86-8(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-indole-4-carboxaldehyde(1074-86-8)

Description and Uses

4-Indolecarbaldehyde is a synthetic intermediate used for pharmaceutical synthesis. Also used as reactant in Biginelli reaction, synthesis of aurora kinase A inhibitors, preparation of antitumor agents, intermolecular Friedel-Crafts acylation, preparation of inhibitors of cell division in E. coli and synthesis of Hantzsch pyridine-containing Schiff bases.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H317-H319
• Precautionary statements: P280-P301+P312+P330-P302+P352-P305+P351+P338
• Hazard Codes: Xn,Xi
• Risk Statements: 22-36-43
• Safety Statements: 26-36/37
• WGK Germany: 3
• Hazard Note: Irritant/Keep Cold
• HazardClass: IRRITANT
• HS Code: 29333990