(S)-(+)-1,2-Isopropylideneglycerol , >98.0%(GC) , 22323-82-6

Synonym(s):
(S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol;D-α,β-Isopropylideneglycerol;D-(+)-Solketal;D-1,2-O-isopropylidene-sn-glycerol;1,2-Isopropylidene-sn-glycerol

CAS NO.：22323-82-6

Empirical Formula: C6H12O3

Molecular Weight: 132.16

MDL number: MFCD00063239

EINECS: 244-910-8

PRODUCT Properties

• alpha: 11 º (c=5, CH3OH)
• Boiling point: 82-83 °C14 mm Hg(lit.)
• Density: 1.07 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.434
• Flash point: 176 °F
• storage temp.: 2-8°C
• solubility: Chloroform, Ethanol, Methanol
• pka: 14.20±0.10(Predicted)
• form: Liquid
• color: Clear colorless to light yellow
• Specific Gravity: 1.07
• optical activity: [α]20/D +13.5°, neat
• Water Solubility: miscible
• Merck: 14,5213
• BRN: 80118
• Stability: Stable. Flammable. Incompatible with oxidizing agents.
• InChIKey: RNVYQYLELCKWAN-YFKPBYRVSA-N
• CAS DataBase Reference: 22323-82-6(CAS DataBase Reference)
• NIST Chemistry Reference: L-Acetone glycerol(22323-82-6)

Description and Uses

(S)-(+)-2,3-O-Isopropylideneglycerol acts as a MEK inhibitor with antitumor activity. It is also employed in the preparation of a chiral allylic triol through extrusion of sulfur dioxide from an alfa,beta-epoxysulfone.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H227
• Precautionary statements: P210e-P280a-P370+P378a-P501a-P210-P280-P370+P378-P403+P235-P501
• Safety Statements: 23-24/25
• WGK Germany: 3
• RTECS: JI0400000
• F: 10
• HS Code: 29329970