Indole-5-boronic acid , ≥95.0% , 144104-59-6

Synonym(s):
5-Indoleboronic acid;Indole-5-boronic acid

CAS NO.：144104-59-6

Empirical Formula: C8H8BNO2

Molecular Weight: 160.97

MDL number: MFCD01319013

PRODUCT Properties

• Melting point: 170-175 °C
• Boiling point: 433.2±37.0 °C(Predicted)
• Density: 1.33±0.1 g/cm3(Predicted)
• storage temp.: 2-8°C
• pka: 8.91±0.30(Predicted)
• form: Crystalline Powder
• color: White
• Sensitive: Air Sensitive
• CAS DataBase Reference: 144104-59-6(CAS DataBase Reference)

Description and Uses

Reactant involved in the synthesis of biologically active molecules including:

• Indole inhibitors of MMP-13 for arthritic disease treatment
• Substituted pyrimidines acting as tubulin polymerization inhibitors

Reactant involved in Suzuki coupling reactions for synthesis of

• Aryl- hetarylfurocoumarins
• Aryl-substituted oxabenzindoles and methanobenzindoles

Reactant involved in:

• Oxidative cross-coupling with mercaptoacetylenes
• Trifluoromethylation

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi,Xn
• Risk Statements: 36/37/38-21/22
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• Hazard Note: Irritant/Keep Cold
• HazardClass: IRRITANT, KEEP COLD
• HS Code: 29339900