A5048012
<I>trans</I>-1-Acetyl-4-hydroxy-<SC>L</SC>-proline , 99% , 33996-33-7
Synonym(s):
N-Acetyl-L -hydroxyproline
CAS NO.：33996-33-7
Empirical Formula: C7H11NO4
Molecular Weight: 173.17
MDL number: MFCD00037339
EINECS: 251-780-6
| Pack Size | Price | Stock | Quantity |
| 10G | RMB304.00 | In Stock |
|
| 25g | RMB564.80 | In Stock |
|
| 50G | RMB767.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 132-133 °C (dec.)(lit.) |
| alpha | -119 º (c=4 in H2O) |
| Boiling point: | 303.8°C (rough estimate) |
| Density | 1.3346 (rough estimate) |
| vapor pressure | 0Pa at 20℃ |
| refractive index | 1.4490 (estimate) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMSO : ≥ 32 mg/mL (184.79 mM) |
| form | Crystalline Powder |
| pka | 3.48±0.40(Predicted) |
| color | White |
| optical activity | [α]20/D 119°, c = 4 in H2O |
| Merck | 14,6903 |
| BRN | 84043 |
| Major Application | peptide synthesis |
| Cosmetics Ingredients Functions | HUMECTANT SKIN PROTECTING SKIN CONDITIONING SKIN CONDITIONING - EMOLLIENT HAIR CONDITIONING |
| InChI | 1S/C7H11NO4/c1-4(9)8-3-5(10)2-6(8)7(11)12/h5-6,10H,2-3H2,1H3,(H,11,12)/t5-,6+/m1/s1 |
| InChIKey | BAPRUDZDYCKSOQ-RITPCOANSA-N |
| SMILES | CC(=O)N1C[C@H](O)C[C@H]1C(O)=O |
| LogP | -1.51 at 20℃ |
| CAS DataBase Reference | 33996-33-7(CAS DataBase Reference) |
| EPA Substance Registry System | L-Proline, 1-acetyl-4-hydroxy-, (4R)- (33996-33-7) |
Description and Uses
trans-1-Acetyl-4-hydroxy-L-proline can be used:
- In the stereospecific synthesis of 4-fluoroglutamic acid.
- To synthesize molecular targets for von Hippel-Lindau (VHL) E3 ubiquitin ligase.
- As a precursor to synthesize pseudopoly(amino acids) such as poly(trans-4-hydroxy-4-acyl-L-proline ester) and a biodegradable polymer, poly(lactic acid-glycolic acid-4-hydroxyproline).
Safety
| Symbol(GHS) |  GHS05 |
| Signal word | Danger |
| Hazard statements | H318 |
| Precautionary statements | P280-P305+P351+P338 |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 41 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| F | 10 |
| TSCA | TSCA listed |
| HS Code | 29339900 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Dam. 1 |
