PRODUCT Properties
| Melting point: | 44-46 °C (lit.) |
| Boiling point: | 225 °C/100 mmHg (lit.) |
| Density | 0.883 g/mL at 25 °C (lit.) |
| bulk density | 490kg/m3 |
| vapor pressure | 1 mm Hg ( 121 °C) |
| FEMA | 2614 | LAURIC ACID |
| refractive index | 1.4304 |
| Flash point: | >230 °F |
| storage temp. | 2-8°C |
| solubility | 4.81mg/l |
| form | Crystalline Powder of Flakes |
| pka | pKa 4.92(H2O,t =25.0) (Uncertain) |
| Specific Gravity | 0.883 |
| color | White |
| Odor | at 100.00 %. mild fatty coconut bay oil |
| Odor Type | fatty |
| biological source | plant |
| explosive limit | 0.6%(V) |
| Water Solubility | insoluble |
| λmax | 207nm(MeOH)(lit.) |
| JECFA Number | 111 |
| Merck | 14,5384 |
| BRN | 1099477 |
| Stability: | Stable. Combustible. Incompatible with bases, oxidizing agents, reducing agents. |
| InChIKey | POULHZVOKOAJMA-UHFFFAOYSA-N |
| LogP | 5 |
| Dissociation constant | 5.3 at 20℃ |
| CAS DataBase Reference | 143-07-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Dodecanoic acid(143-07-7) |
| EPA Substance Registry System | Lauric acid (143-07-7) |
Description and Uses
Lauric acid, also known as dodecanoic acid, is a saturated fatty acid with a 12-carbon atom chain, thus falling into the medium chain fatty acids, is a white crystalline carboxylic acid with a faint odor of bay oil or soap. It has been found at high levels in coconut oil. Lauric acid induces the activation of NF-κB and the expression of COX-2, inducible nitric oxide synthase (iNOS), and IL-1α in RAW 264.7 cells when used at a concentration of 25 μM.
Lauric Acid is a fatty acid obtained from coconut oil and other veg- etable fats. it is practically insoluble in water but is soluble in alco- hol, chloroform, and ether. it functions as a lubricant, binder, and defoaming agent.
Safety
| Symbol(GHS) |  GHS05 |
| Signal word | Danger |
| Hazard statements | H318 |
| Precautionary statements | P280-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/38-41-36/37/38 |
| Safety Statements | 37/39-26-39-36-36/39-24/25 |
| WGK Germany | 1 |
| RTECS | OE9800000 |
| Autoignition Temperature | 250 °C |
| TSCA | Yes |
| HS Code | 29159010 |
| Hazardous Substances Data | 143-07-7(Hazardous Substances Data) |
| Toxicity | LD50 i.v. in mice: 131 ±5.7 mg/kg (Or, Wretlind) |
