A5291712
LDE225 (NVP-LDE225,Erismodegib) , ≥99% , 956697-53-3
CAS NO.：956697-53-3
Empirical Formula: C26H26F3N3O3
Molecular Weight: 485.5
MDL number: MFCD16038928
EINECS: 1312995-182-4
| Pack Size | Price | Stock | Quantity |
| 10MG | RMB332.80 | In Stock |
|
| 50MG | RMB1471.20 | In Stock |
|
| 100mg | RMB2495.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 154-157°C |
| Boiling point: | 544.5±50.0 °C(Predicted) |
| Density | 1.255 |
| storage temp. | Refrigerator |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | White solid. |
| pka | 9.53±0.70(Predicted) |
| color | Light Purple |
| InChIKey | VZZJRYRQSPEMTK-CALCHBBNNA-N |
| SMILES | C1(C2=CC=C(OC(F)(F)F)C=C2)=CC=CC(C(NC2=CC=C(N3C[C@H](C)O[C@H](C)C3)N=C2)=O)=C1C |&1:24,27,r| |
Description and Uses
A potent, selective and orally bioavailable Smoothened (SMO) antagonist; it inhibits hedgehog (Hh) signaling pathway via antagonism of the Smoothened receptor (SMO). Antineoplastic. Potent Hedgehog inhibitor.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P271-P280-P261 |
| HS Code | 2934999090 |
