A5292112
LY2811376 , ≥99% , 1194044-20-6
CAS NO.：1194044-20-6
Empirical Formula: C15H14F2N4S
Molecular Weight: 320.36
MDL number: MFCD18074525
| Pack Size | Price | Stock | Quantity |
| 5MG | RMB808.80 | In Stock |
|
| 10MG | RMB1439.20 | In Stock |
|
| 50MG | RMB5071.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 486.5±55.0 °C(Predicted) |
| Density | 1.42 |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| form | crystalline solid |
| pka | 5.60±0.40(Predicted) |
| color | White to khaki |
| InChI | InChI=1S/C15H14F2N4S/c1-15(2-3-22-14(18)21-15)11-4-10(12(16)5-13(11)17)9-6-19-8-20-7-9/h4-8H,2-3H2,1H3,(H2,18,21)/t15-/m0/s1 |
| InChIKey | MJQMRGWYPNIERM-HNNXBMFYSA-N |
| SMILES | S1CC[C@](C2=CC(C3=CN=CN=C3)=C(F)C=C2F)(C)N=C1N |
Description and Uses
LY 281137 is a compound capable of the decrease in β-amyloid peptide (Aβ) associated with the cleavage of amyloid precursor protein (APP) by β-secretase (BACE) and γ-secretase. This decrease is important as its hypothesized that the build up of (Aβ) in the brain is a primary cause of neurodegeneration and Alzheimer’s progression.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501 |
