A5318512
Locostatin , 98%(HPLC) , 90719-30-5
| Pack Size | Price | Stock | Quantity |
| 10MG | RMB503.20 | In Stock |
|
| 50MG | RMB1759.20 | In Stock |
|
| 250mg | RMB5599.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 84-88 °C(lit.) |
| Boiling point: | 351.0±25.0 °C(Predicted) |
| Density | 1.205±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: ≥30mg/mL |
| pka | -1?+-.0.40(Predicted) |
| form | powder |
| color | white to off-white |
Description and Uses
Locostatin (UIC-1005) is a potent RKIP inhibitor. Locostatin binds Raf kinase inhibitor RKIP protein and disrupts the interaction of RKIP with Raf-1 kinase and G protein-coupled receptor kinase 2. Locostatin inhibits cell proliferation and migration. Locostatin can be used to synthesize chemical probes toward PEBP-proteins. Locostatin aggravates thioacetamide (HY-Y0698)-induced acute liver failure in mice [1][2][3].
Safety
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| HS Code | 29349990 |
