A5398412
(1R,2S,5R)-(−)-Menthol , Analysis of standard products, used for pyrene analysis, ≥99.5%(GC) , 2216-51-5
Synonym(s):
(-)-Menthol;(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol;2-Isopropyl-5-methylcyclohexanol;(?)-Menthol;(1R,2S,5R)-(?)-Menthol
CAS NO.：2216-51-5
Empirical Formula: C10H20O
Molecular Weight: 156.27
MDL number: MFCD00062979
EINECS: 218-690-9
| Pack Size | Price | Stock | Quantity |
| 1G | RMB95.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 41-45 °C (lit.) |
| alpha | -51 º (589nm, c=10, EtOH) |
| Boiling point: | 212 °C (lit.) |
| bulk density | 450kg/m3 |
| Density | 0.89 g/mL at 25 °C (lit.) |
| vapor pressure | 0.8 mm Hg ( 20 °C) |
| refractive index | 1.46 |
| FEMA | 2665 | MENTHOL RACEMIC |
| Flash point: | 200 °F |
| storage temp. | Store below +30°C. |
| solubility | 490mg/l |
| pka | 15.30±0.60(Predicted) |
| form | Crystals or Crystalline Needles |
| color | Colorless to white |
| Specific Gravity | 0.89 |
| Odor | at 10.00 % in dipropylene glycol. peppermint cooling mentholic minty |
| Odor Type | mentholic |
| optical activity | [α]22/D 49°, c = 10 in 95% ethanol |
| biological source | synthetic (organic) |
| Water Solubility | insoluble |
| Merck | 14,5837 |
| BRN | 1902293 |
| Henry's Law Constant | 6.6×10-1 mol/(m3Pa) at 25℃, HSDB (2015) |
| Dielectric constant | 3.2（Ambient） |
| Stability: | Stable. |
| Major Application | flavors and fragrances |
| Cosmetics Ingredients Functions | DENATURANT REFRESHING SOOTHING FRAGRANCE |
| InChI | 1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3/t8-,9+,10-/m1/s1 |
| InChIKey | NOOLISFMXDJSKH-KXUCPTDWSA-N |
| SMILES | CC(C)[C@@H]1CC[C@@H](C)C[C@H]1O |
| LogP | 3.15 at 25℃ |
| CAS DataBase Reference | 2216-51-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Cyclohexanol, 5-methyl-2-(1-methylethyl)-, [1R-(1«alpha»,2«beta»,5«alpha»)]-(2216-51-5) |
| EPA Substance Registry System | Levomenthol (2216-51-5) |
Description and Uses
L-Menthol is used as a cooling agent that strongly activates TRPM8.(Transient Receptor Potential Cation Channel, Subfamily M, Member 8 is a Protein Coding gene). It is used as analgesic (topical), antipruritic agent. It is used as: refreshing agent, food flavor, cool and antipruritic drug, carminative drug. Menthol crystals is used for pers onal care and cosmetics.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313 |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 37/38-41-36/37/38 |
| Safety Statements | 26-39-37/39-36 |
| WGK Germany | 2 |
| RTECS | OT0700000 |
| TSCA | TSCA listed |
| HS Code | 29061100 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 |
| Hazardous Substances Data | 2216-51-5(Hazardous Substances Data) |
| Toxicity | LD50 orally in Rabbit: 3300 mg/kg LD50 dermal Rabbit > 5000 mg/kg |
| REACH Registrations | Active |
