ClothianidinSolutioninAcetonitrile , 1000μg/mLinAcetonitrile,uncertainty2% , 210880-92-5

Synonym(s):
(E)-1-(2-Chloro-5-thiazolylmethyl)-3-methyl-2-nitroguanidine

CAS NO.：210880-92-5

Empirical Formula: C6H8ClN5O2S

Molecular Weight: 249.67

MDL number: MFCD06200753

EINECS: 205-516-1

PRODUCT Properties

• Melting point: 178.8 °C
• Boiling point: 412.5±55.0 °C(Predicted)
• Density: 1.61
• vapor pressure: 0Pa at 25℃
• storage temp.: 0-6°C
• solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.50 mg/ml
• pka: 2.76±0.50(Predicted)
• form: Solid
• color: Off-white to light yellow
• Water Solubility: 327 mg/L at 20 ºC
• Henry's Law Constant: 3.4×10¹⁰ mol/(m³Pa) at 25℃, MacBean (2012)
• Major Application: agriculture; environmental
• InChI: 1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11)
• InChIKey: PGOOBECODWQEAB-UHFFFAOYSA-N
• SMILES: CN\C(NCc1cnc(Cl)s1)=N/[N+]([O-])=O
• LogP: 0.7 at 25℃
• CAS DataBase Reference: 210880-92-5
• EPA Substance Registry System: Clothianidin (210880-92-5)

Description and Uses

Clothianidin is an insecticide for the control of sucking and chewing pests. It is moderately soluble and volatile but has a high potential for leaching to groundwater. It is very persistent in soil and water. Risk of bioaccumulation is low and its acute toxicity to mammals is considered moderate. It is, however, a neurotoxicant. It is toxic to some aquatic organisms but not greatly so to fish. It is highly toxic to honeybees but low risk to earthworms.

Insecticide.

Safety

• Symbol(GHS): GHS07,GHS09
• Signal word: Warning
• Hazard statements: H302-H410
• Precautionary statements: P273-P301+P312+P330
• PPE: Eyeshields, Gloves, type N95 (US)
• Hazard Codes: Xn,N
• Risk Statements: 22-50/53
• Safety Statements: 46-60-61
• RIDADR: UN 3077 9 / PGIII
• WGK Germany: 1
• RTECS: ME9565000
• HS Code: 29341000
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Acute Tox. 4 Oral; Aquatic Acute 1; Aquatic Chronic 1
• Hazardous Substances Data: 210880-92-5(Hazardous Substances Data)
• Toxicity: LD50 in rats (mg/kg): >5000 orally; >2000 dermally; LC50 in rats (mg/l): >6.1 inhalation; LC50 in bobwhite quail, mallard duck (ppm): >5200, >5200 (dietary); LC50 (96 hr) in rainbow trout, bluegill (mg/l): >100, >120 (Ohkawara)
• REACH Registrations: Active