A5409012
4-Methyl-2-pentanone , standardforGC,≥99.5%(GC) , 108-10-1
Synonym(s):
MIBK;Methyl isobutyl ketone;4-Methyl-2-pentanone;MIK;Isobutyl methyl ketone
CAS NO.：108-10-1
Empirical Formula: C6H12O
Molecular Weight: 100.16
MDL number: MFCD00008938
EINECS: 203-550-1
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | -80 °C (lit.) |
| Boiling point: | 117-118 °C |
| Density | 0.801 g/mL at 25 °C (lit.) |
| vapor density | 3.5 (vs air) |
| vapor pressure | 15 mm Hg ( 20 °C) |
| refractive index | n |
| FEMA | 2731 | 4-METHYL-2-PENTANONE |
| Flash point: | 56 °F |
| storage temp. | Store at +5°C to +30°C. |
| solubility | water: soluble20g/L, soluble in alcohol, miscible with oils. Soluble in Propylene glycol and Glycerin. |
| form | Liquid |
| color | APHA: ≤15 |
| Specific Gravity | 0.80 |
| Odor | Pleasant; mild, characteristic; sharp; non-residual; ketonic. |
| PH | 7 (20°C) |
| Odor Threshold | 0.17ppm |
| Odor Type | green |
| biological source | synthetic |
| explosive limit | 1.2-8%, 93°F |
| Water Solubility | 17 g/L (20 ºC) |
| λmax | λ: 335 nm Amax: 1.00 λ: 340 nm Amax: 0.50 λ: 360 nm Amax: 0.15 λ: 380 nm Amax: 0.02 λ: 400 nm Amax: 0.01 |
| Merck | 14,5207 |
| JECFA Number | 301 |
| BRN | 605399 |
| Henry's Law Constant | 2.56 at 25 °C (batch stripping method-GC, Kim et al., 2000) |
| Exposure limits | ACGIH:TLV-TWA 20 ppm (82 mg/m3); TLV-STEL 75 ppm (307 mg/m3) OSHA:PEL-TWA 100 ppm (410 mg/m3) NIOSH:REL-TWA 50 ppm; REL-STEL 75 ppm |
| Dielectric constant | 13.0（Ambient） |
| Stability: | Volatile |
| Cosmetics Ingredients Functions | SOLVENT PERFUMING DENATURANT |
| Cosmetic Ingredient Review (CIR) | 4-Methyl-2-pentanone (108-10-1) |
| InChI | 1S/C6H12O/c1-5(2)4-6(3)7/h5H,4H2,1-3H3 |
| InChIKey | NTIZESTWPVYFNL-UHFFFAOYSA-N |
| SMILES | CC(C)CC(C)=O |
| LogP | 1.3-1.9 at 20℃ |
| CAS DataBase Reference | 108-10-1(CAS DataBase Reference) |
| IARC | 2B (Vol. 101) 2013 |
| NIST Chemistry Reference | Methyl isobutyl ketone(108-10-1) |
| EPA Substance Registry System | Methyl isobutyl ketone (108-10-1) |
| ECETOC JACC REPORT | 4-Methyl-2-pentanone (108-10-1) |
Description and Uses
4-Methyl-2-pentanone has a pleasant odor. May be prepared by hydrogenation of mesityl oxide over Ni at 160 - 190°C; also by oxidation of methyl isobutyl carbinol.
In paints, glues, and cleaning agents; used in the plastic and petrol industries
Safety
| Symbol(GHS) |    GHS02,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H332-H303-H319-H372-H351-H335-H336-H225 |
| Precautionary statements | P501-P260-P270-P202-P240-P210-P233-P201-P243-P241-P242-P271-P264-P280-P370+P378-P312-P337+P313-P305+P351+P338-P303+P361+P353-P304+P340+P312-P403+P233-P403+P235-P405 |
| target organs | Central nervous system |
| Hazard Codes | F,Xn,T |
| Risk Statements | 11-20-36/37-66-39/23/24/25-23/24/25 |
| Safety Statements | 9-16-29-45-36/37-7 |
| RIDADR | UN 1245 |
| OEB | A |
| OEL | TWA: 50 ppm (205 mg/m3), STEL: 75 ppm (300 mg/m3) |
| WGK Germany | 1 |
| RTECS | SA9275000 |
| Autoignition Temperature | 840 °F |
| TSCA | TSCA listed |
| HS Code | 2914 13 00 |
| HazardClass | 3 |
| PackingGroup | II |
| Storage Class | 3 - Flammable liquids |
| Hazard Classifications | Acute Tox. 4 Inhalation Carc. 2 Inhalation Eye Irrit. 2 Flam. Liq. 2 STOT SE 3 |
| Hazardous Substances Data | 108-10-1(Hazardous Substances Data) |
| Toxicity | LD50 orally in rats: 2.08 g/kg (Smyth) |
| IDLA | 500 ppm |
| REACH Registrations | Active |
| Limited Quantities | 1.0 L (0.3 gallon) (liquid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) |
