4-(2-Aminoethyl)morpholine , 98% , 2038-03-1

Synonym(s):
2-Morpholinoethylamine

CAS NO.：2038-03-1

Empirical Formula: C6H14N2O

Molecular Weight: 130.19

MDL number: MFCD00006182

EINECS: 218-011-6

PRODUCT Properties

• Melting point: 24 °C
• Boiling point: 205 °C(lit.)
• Density: 0.992 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.476(lit.)
• Flash point: 347 °F
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: soluble in Chloroform, Methanol
• pka: pK1: 4.06(+2);pK2: 9.15(+1) (25°C)
• form: Liquid After Melting
• color: Clear colorless to pale yellow
• Water Solubility: soluble
• Sensitive: Air Sensitive
• BRN: 104378
• Stability: Air Sensitive
• InChIKey: RWIVICVCHVMHMU-UHFFFAOYSA-N
• CAS DataBase Reference: 2038-03-1(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Morpholineethanamine(2038-03-1)
• EPA Substance Registry System: 4-Morpholineethanamine (2038-03-1)

Description and Uses

4-(2-Aminoethyl)morpholine is widely used in biomedical applications as this moiety serves as an important lysosome-targeting group. Some of its applications include:

• Synthesis of the lysosome-targetable fluorescent probe for hydrogen sulfide imaging in living cells.
• Synthesis of 1,8-naphthalimide conjugated Troger′s bases as deoxyribonucleic acid (DNA) targeting fluorescent probe.
• Synthesis of intramolecular charge transfer-photoinduced electron transfer-fluorescence resonance energy transfer (ICT-PET-FRET) fluorescent probe for monitoring pH changes in living cells.
• It is also used as a precursor to synthesize a variety of antimicrobial agents.

Safety

• Symbol(GHS): GHS05,GHS07
• Signal word: Danger
• Hazard statements: H302-H314-H317
• Precautionary statements: P260-P270-P280-P301+P312-P303+P361+P353-P305+P351+P338
• Hazard Codes: C,T
• Risk Statements: 22-34-43-24-40-23/24/25
• Safety Statements: 26-36/37/39-45-22
• RIDADR: UN 2735 8/PG 2
• WGK Germany: 2
• RTECS: QD7350000
• Hazard Note: Toxic
• TSCA: Yes
• HazardClass: 8
• PackingGroup: III
• HS Code: 29349990
• Toxicity: guinea pig,LD50,skin,300uL/kg (0.3mL/kg),Journal of Industrial Hygiene and Toxicology. Vol. 26, Pg. 269, 1944.