A5446812
Magnolin , Analysis of standard products, ≥98% , 31008-18-1
Synonym(s):
(+)-Magnolin;(1S,3aR,4S,6aR)-1-(3,4-Dimethoxyphenyl)tetrahydro-4-(3,4,5-trimethoxyphenyl)-1H,3H-furo[3,4-c]furan;(1S,3aR,4S,6aR)-1-(3,4-Dimethoxyphenyl)tetrahydro-4-(3,4,5-trimethoxyphenyl)-1H,3H-furo[3,4-c]furan;Magnolin;Medioresinol dimethyl ether
| Pack Size | Price | Stock | Quantity |
| 20MG | RMB614.40 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 91.4-92.9 °C |
| Boiling point: | 536.9±50.0 °C(Predicted) |
| Density | 1.178±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| form | Solid |
| color | White to Off-White |
| optical activity | [α]/D +46 to +56°, c =0.5 in chloroform-d |
| InChIKey | MFIHSKBTNZNJIK-RZTYQLBFSA-N |
| SMILES | O1C[C@]2([H])[C@@H](C3=CC(OC)=C(OC)C(OC)=C3)OC[C@]2([H])[C@H]1C1=CC=C(OC)C(OC)=C1 |
Description and Uses
Magnolin, a major component of Magnolia flos (Shin-Yi), inhibits the Ras/ERKs/RSK2 signaling axis by targeting the active pocket of ERK1 and ERK2 with IC50s of 87 nM and 16.5 nM, respectively.
Magnolin is a lignan extract from Magnoliae Flos, displaying anti-asthma and anti-inflammatory activity.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Safety Statements | 24/25 |
| HS Code | 29329990 |
