A6220512
N-octanoyl-D-erythro-sphingosine , >99% , 74713-59-0
| Pack Size | Price | Stock | Quantity |
| 5MG | RMB1279.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 68-70°C |
| Boiling point: | 541.37°C (rough estimate) |
| Density | 0.9974 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | −20°C |
| solubility | DMSO or ethanol: soluble |
| form | waxy solid |
| color | White |
| Stability: | Temperature Sensitive |
| InChIKey | APDLCSPGWPLYEQ-WRBRXSDHSA-N |
| SMILES | C(N[C@@H](CO)[C@H](O)/C=C/CCCCCCCCCCCCC)(=O)CCCCCCC |
| CAS DataBase Reference | 74713-59-0(CAS DataBase Reference) |
Description and Uses
C8-ceramide (74713-59-0) is a cell permeable ceramide analog. Stimulates ceramide-activated protein kinase.1?Induces apoptosis.2?Reported to inhibit apoptosis and gap junction intercellular communication (GJIC) in rat liver epithelial cells.3?C8-ceramide induces the secretion of brain-derived neurotrophic factor (BDNF) from microglia?in vitro.4
A biologically active, cell permeable, but nonphysiologic ceramide analog. It induces phosphorylation on Thr-669 in A-431 cells by stimulation of ceramide-activated protein kinase. It stimulates IL-2 secretion and induces apoptosis
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| HS Code | 29225000 |
