(R)-(-)-N-(2,3-Epoxypropyl)phthalimide , ≥98.0%(GC) , 181140-34-1

Synonym(s):
(R)-N-Glycidylphthalimide

CAS NO.：181140-34-1

Empirical Formula: C11H9NO3

Molecular Weight: 203.19

MDL number: MFCD04973349

EINECS: 629-091-0

PRODUCT Properties

• Melting point: 101 °C
• Boiling point: 347.4±15.0 °C(Predicted)
• Density: 1.446±0.06 g/cm3 (20 ºC 760 Torr)
• refractive index: -10 ° (C=2.2, CHCl3)
• storage temp.: Inert atmosphere,Room Temperature
• solubility: Chloroform (Slightly), Methanol (Slightly)
• form: Solid
• pka: -2.24±0.20(Predicted)
• color: White
• optical activity: [α]/D -7 to -13°, c =2.2 in chloroform
• InChI: 1S/C11H9NO3/c13-10-8-3-1-2-4-9(8)11(14)12(10)5-7-6-15-7/h1-4,7H,5-6H2/t7-/m1/s1
• InChIKey: DUILGEYLVHGSEE-SSDOTTSWSA-N
• SMILES: O=C1N(C[C@@H]2CO2)C(=O)c3ccccc13

Description and Uses

(R)-(-)-N-(2,3-Epoxypropyl)phthalimide may be used in the preparation of the following potential chiral solvating agents:

• 2-[(2R)-2-hydroxy-3-[[(1R)-2-hydroxy-1-phenyl-ethyl]amino]propyl] isoindoline-1,3-dione
• 2-[(2R)-2-hydroxy-3-[[(1R,2S)-2-hydroxyindan-1-yl]amino]propyl]isoindoline-1,3-dione
• 2-[(2R)-2-hydroxy-3-[[(1R)-1-(hydroxymethyl)-propyl]amino]propyl] isoindoline-1,3-dione
• 2-[(2R)-2-hydroxy-3-[[(1S)-1-phenylethyl]-amino]propyl]isoindoline-1,3-dione

It may also be used in the synthesis of 2-((5R)-2-oxo-5-oxazolidinyl) methyl)-1H-isoindole-1,3 (2H)-dione.

Safety

• Symbol(GHS): GHS05
• Signal word: Danger
• Hazard statements: H318
• Precautionary statements: P280-P305+P351+P338
• PPE: dust mask type N95 (US), Eyeshields, Gloves
• Hazard Codes: Xi
• Risk Statements: 41
• Safety Statements: 26-39
• WGK Germany: 2
• HS Code: 29251900
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Eye Dam. 1