<i>N</i>-(Pyrazinylcarbonyl)-<small>L</small>-phenylalanine , >98.0%(HPLC) , 114457-94-2

CAS NO.：114457-94-2

Empirical Formula: C14H13N3O3

Molecular Weight: 271.27

MDL number: MFCD09800536

PRODUCT Properties

• Melting point: 166-169℃
• Boiling point: 573.8±50.0 °C(Predicted)
• Density: 1.323
• storage temp.: Sealed in dry,Room Temperature
• solubility: DMSO, Methanol (Sparingly)
• pka: 13.93±0.46(Predicted)
• form: Solid
• color: White to Light Beige
• InChI: InChI=1S/C14H13N3O3/c18-13(12-9-15-6-7-16-12)17-11(14(19)20)8-10-4-2-1-3-5-10/h1-7,9,11H,8H2,(H,17,18)(H,19,20)/t11-/m0/s1
• InChIKey: DWYZPDHMMZGQAP-NSHDSACASA-N
• SMILES: C(O)(=O)[C@H](CC1=CC=CC=C1)NC(C1=NC=CN=C1)=O

Description and Uses

(S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID is used for the synthesis of Bortezomib (B675700) from L-phenylalanine via dipeptidyl boronic acid ester intermediates.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• HS Code: 2933998090