Oleamide , 70% , 301-02-0

Synonym(s):
cis-9,10-Octadecenoamide;cis-9-Octadecenamide;Oleic acid amide

CAS NO.：301-02-0

Empirical Formula: C18H35NO

Molecular Weight: 281.48

MDL number: MFCD00053638

EINECS: 206-103-9

PRODUCT Properties

• Melting point: 70°C
• Boiling point: 433.3±24.0 °C(Predicted)
• Density: 0.94 g/cm3
• storage temp.: -20°C
• solubility: Soluble in chloroform (50 mg/ml), ethanol (100 mM), DMSO (~14 mg/ml), and DMF (~14 mg/ml)
• form: Solid
• pka: 16.61±0.40(Predicted)
• color: White to off-white
• Water Solubility: Insoluble in water.
• Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
• InChIKey: FATBGEAMYMYZAF-KTKRTIGZSA-N
• LogP: 6.882 (est)
• CAS DataBase Reference: 301-02-0(CAS DataBase Reference)
• NIST Chemistry Reference: 9-Octadecenamide, (z)-(301-02-0)
• EPA Substance Registry System: Oleamide (301-02-0)

Description and Uses

OOleamide (301-02-0) was originally identified in the cerebrospinal fluid of sleep-deprived cats acting as an inducer of physiological sleep in animals.1 Displays agonist activity at cannabinoid CB1 receptors (Ki=8.13 μM).2 Activates PPARγ.3 Produces vasodilator effects in rats.4 Displays neuroprotective effects5 and attenuates sepsis-induced intestinal injury6.

A brain lipid that induces physiological sleep at nanomolar quantities when injected into rats. This lipid may represent a new class of biological signaling molecules.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H413
• Precautionary statements: P273-P501
• Hazard Codes: Xi
• Risk Statements: 36/37/38-43
• Safety Statements: 26-36-37
• WGK Germany: 1
• HS Code: 29241990
• Hazardous Substances Data: 301-02-0(Hazardous Substances Data)