Phenyl chloroformate , 98% , 1885-14-9

Synonym(s):
Chloroformic acid phenyl ester;Chloroformic acid phenyl ester, Phenyl chlorocarbonate;Phenyl chloroformate

CAS NO.：1885-14-9

Empirical Formula: C7H5ClO2

Molecular Weight: 156.57

MDL number: MFCD00000637

EINECS: 217-547-8

PRODUCT Properties

• Melting point: -28 °C
• Boiling point: 74-75 °C/13 mmHg (lit.)
• Density: 1.248 g/mL at 25 °C (lit.)
• vapor density: 1 (vs air)
• vapor pressure: 1.22 psi ( 20 °C)
• refractive index: n20/D 1.511(lit.)
• Flash point: 168 °F
• storage temp.: 2-8°C
• solubility: Miscible with N,N-dimethylformamide.
• form: Liquid
• color: Clear
• Water Solubility: hydrolysis
• Sensitive: Moisture Sensitive
• BRN: 606778
• CAS DataBase Reference: 1885-14-9(CAS DataBase Reference)
• NIST Chemistry Reference: Carbonochloridic acid, phenyl ester(1885-14-9)
• EPA Substance Registry System: Carbonochloridic acid, phenyl ester (1885-14-9)

Description and Uses

Phenyl chloroformate is used in the synthesis of poly(2-(phenoxycarbonyloxy)ethyl methacrylate) and phenyl-(4-vinylphenyl) carbonate. It acts as a precursor of phenyl mixed anhydrides which are used in peptide coupling reactions. It serves as a dehydrating reagent for the conversion of primary amides to nitriles and an intermediate in the synthesis of pharmaceuticals and carbamates.

Safety

• Symbol(GHS): GHS05,GHS06
• Signal word: Danger
• Hazard statements: H290-H302-H314-H330-H335
• Precautionary statements: P234-P280-P301+P312-P303+P361+P353-P304+P340+P310-P305+P351+P338
• Hazard Codes: T+
• Risk Statements: 22-26-34-41-38-29-37
• Safety Statements: 26-28-36/37/39-45-28A
• RIDADR: UN 2746 6.1/PG 2
• WGK Germany: 3
• RTECS: FG3850000
• F: 10-19-21
• Autoignition Temperature: 540 °C
• TSCA: Yes
• HazardClass: 6.1
• PackingGroup: II
• HS Code: 29159020
• Toxicity: LD50 orally in Rabbit: 1730 mg/kg LD50 dermal Rabbit 4880 mg/kg
• Limited Quantities: 100ml (liquid) or 0.5 Kg (solid)
• Excepted Quantities: Max Inner Pack (1g or 1ml) and Max Outer Pack (500g or 500ml)