D-(-)-α-Phenylglycine , 99% , 875-74-1

Synonym(s):
(R)-(−)-2-Phenylglycine;D-2-Phenylglycine;R-(−)-α-Aminophenylacetic acid

CAS NO.：875-74-1

Empirical Formula: C8H9NO2

Molecular Weight: 151.16

MDL number: MFCD00008061

EINECS: 212-876-3

PRODUCT Properties

• Melting point: 302 °C (dec.)(lit.)
• Boiling point: 273.17°C (rough estimate)
• alpha: -156 º (c=1,1N HCl)
• Density: 1.2 g/cm3 (20℃)
• vapor pressure: 0Pa at 25℃
• refractive index: -158 ° (C=1, 1mol/L HCl)
• Flash point: 150 °C
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: Aqueous Acid (Sparingly), Water (Slightly, Heated)
• pka: 1.94±0.10(Predicted)
• form: Crystalline Powder
• color: White
• optical activity: [α]20/D 155°, c = 1 in 1 M HCl
• Water Solubility: 0.3g/100mL
• Merck: 14,7291
• BRN: 2208676
• LogP: -1.76 at 20℃
• CAS DataBase Reference: 875-74-1(CAS DataBase Reference)
• NIST Chemistry Reference: d a-Phenylglycine(875-74-1)
• EPA Substance Registry System: Benzeneacetic acid, .alpha.-amino-, (.alpha.R)- (875-74-1)

Description and Uses

d-Phenylglycine is widely used in large quantity as the side chain that makes ampicillin and cephalexin orally acceptable.

D-(-)-2-Phenylglycine (Cefalexin EP Impurity A) is the derivative of glycine (G615990), a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H335-H319-H315
• Precautionary statements: P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
• Hazard Codes: T
• Risk Statements: 23/24/25-36/37/38-22-20
• Safety Statements: 22-24/25-45-36/37/39-26-44-28-7-4
• WGK Germany: 3
• TSCA: Yes
• HS Code: 29224995