Prednisone , 98% , 53-03-2

Synonym(s):
1,4-Pregnadiene-17α,21-diol-3,11,20-trione;17α,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione;1-Cortisone;Dehydrocortisone

CAS NO.：53-03-2

Empirical Formula: C21H26O5

Molecular Weight: 358.43

MDL number: MFCD00003608

EINECS: 200-160-3

PRODUCT Properties

• Melting point: 236-238 °C(lit.)
• alpha: 169 º (c=0.5, dioxane)
• Boiling point: 410.86°C (rough estimate)
• Density: 1.1121 (rough estimate)
• refractive index: 170 ° (C=0.5, Dioxane)
• Flash point: >200℃
• storage temp.: 2-8°C
• solubility: Practically insoluble in water, slightly soluble in ethanol (96 per cent) and in methylene chloride. It shows polymorphism (5.9).
• form: Solid
• pka: 12.36±0.60(Predicted)
• color: White to Off-White
• Water Solubility: 115mg/L(25 ºC)
• Merck: 7722
• BRN: 2065301
• BCS Class: 1?
• Stability: Stable. Incompatible with strong oxidizing agents.
• CAS DataBase Reference: 53-03-2(CAS DataBase Reference)
• IARC: 3 (Vol. 26, Sup 7) 1987
• NIST Chemistry Reference: Prednisone(53-03-2)
• EPA Substance Registry System: Prednisone (53-03-2)

Description and Uses

Prednisone is used for the same indications as cortisone for inflammatory processes, allergies, and adrenal gland insufficiency; however, it is somewhat more active than cortisone and has less of an effect on mineral volume.

Safety

• Symbol(GHS): GHS08
• Signal word: Warning
• Hazard statements: H373
• Precautionary statements: P260
• Hazard Codes: Xn
• Safety Statements: 36/37/39-45-26-16
• Hazardous Substances Data: 53-03-2(Hazardous Substances Data)