A6791612
PF-8380 , ≥98% , 1144035-53-9
Synonym(s):
4-[3-(2,3-Dihydro-2-oxo-6-benzoxazolyl)-3-oxopropyl]-1-piperazinecarboxylic acid (3,5-dichlorophenyl)methyl ester;4-[3-Oxo-3-(2-oxo-2,3-dihydrobenzoxazol-6-yl)propyl]piperazine-1-carboxylic acid 3,5-dichlorobenzyl ester;6-(3-(Piperazin-1-yl)propanoyl)-benzo[d]oxazol-2(3H)-one, Atx Inhibitor III, PF-8380;Autotaxin Inhibitor III, PF-8380 - CAS 1144035-53-9 - Calbiochem
CAS NO.：1144035-53-9
Empirical Formula: C22H21Cl2N3O5
Molecular Weight: 478.33
MDL number: MFCD20527274
| Pack Size | Price | Stock | Quantity |
| 5MG | RMB420.80 | In Stock |
|
| 10MG | RMB639.20 | In Stock |
|
| 50MG | RMB2454.40 | In Stock |
|
| 100MG | RMB4388.80 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Density | 1.419 |
| storage temp. | -20°C |
| solubility | DMSO: soluble5mg/mL, clear (warmed) |
| form | Tan powder |
| pka | 8.74±0.70(Predicted) |
| color | white to beige |
| InChI | InChI=1S/C22H21Cl2N3O5/c23-16-9-14(10-17(24)12-16)13-31-22(30)27-7-5-26(6-8-27)4-3-19(28)15-1-2-18-20(11-15)32-21(29)25-18/h1-2,9-12H,3-8,13H2,(H,25,29) |
| InChIKey | JMSUDQYHPSNBSN-UHFFFAOYSA-N |
| SMILES | N1(C(OCC2=CC(Cl)=CC(Cl)=C2)=O)CCN(CCC(C2C=C3OC(=O)NC3=CC=2)=O)CC1 |
Description and Uses
PF-8380 has been used in biological assays. It has also been used to estimate the role of intestinally-derived lysophosphatidic acid in dyslipidemia and atherosclerosis.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335-H413 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | 3 |
