Pirodavir , ≥98% , 124436-59-5

Synonym(s):
4-[2-[1-(6-Methyl-3-pyridazinyl)-4-piperidinyl]ethoxy]-benzoic acid ethyl ester;Ethyl 4-[2-[1-(6-methyl-3-pyridazinyl)-4-piperidinyl]ethoxy]benzoate;R 77975;R77,975;R-77975

CAS NO.：124436-59-5

Empirical Formula: C21H27N3O3

Molecular Weight: 369.46

MDL number: MFCD00866965

PRODUCT Properties

• Melting point: 124-125℃
• storage temp.: Sealed in dry,Store in freezer, under -20°C
• solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• form: Solid
• color: Off-White to Pale Beige
• InChI: 1S/C21H27N3O3/c1-3-26-21(25)18-5-7-19(8-6-18)27-15-12-17-10-13-24(14-11-17)20-9-4-16(2)22-23-20/h4-9,17H,3,10-15H2,1-2H3
• InChIKey: KCHIOGFOPPOUJC-UHFFFAOYSA-N
• SMILES: O=C(OCC)C1=CC=C(OCCC2CCN(C3=NN=C(C)C=C3)CC2)C=C1

Description and Uses

Pirodavir is a broad-spectrum antipicornaviral agent. It is active against 80 typed (MICs = 0.001-14.4 μg/ml) and one untyped rhinovirus strain (MIC = 0.002 μg/ml) and is active against both group A and group B serotypes. It is also active against serotypes of coxsackievirus, poliovirus, and echovirus enteroviruses (MICs = 0.018-8.5, 0.025-0.27, and 0.019-1.3 μg/ml, respectively).

Pirodavir is used to modulate lipophilicity in human rhinovirus capsid binders. It also is used in order to identify potential ativiral agents.

Safety

• WGK Germany: WGK 3
• HS Code: 2933.99.7500
• Storage Class: 11 - Combustible Solids