Pemetrexed disodium hydrate , 99% , 357166-30-4

CAS NO.：357166-30-4

Empirical Formula: 2(C20H19N5Na2O6).5(H2O)

Molecular Weight: 1032.84

MDL number: MFCD13194950

EINECS: 814-356-7

PRODUCT Properties

• Melting point: 274-276°C (dec.)
• storage temp.: Room Temperature
• solubility: DMSO, Methanol, Water
• form: Solid
• color: Off-White
• InChIKey: AEZRDYKQLPDYEH-YTCXBBKHNA-N
• SMILES: C(C1=CNC2NC(N)=NC(=O)C1=2)CC1C=CC(C(=O)N[C@H](C(=O)O)CCC(=O)O)=CC=1.[NaH].O |&1:20,r|
• CAS DataBase Reference: 357166-30-4(CAS DataBase Reference)

Description and Uses

Pemetrexed Disodium Hydrate is an chemotherapy drug for the treatment of pleural mesothelioma and non-small cell lung cancer. Pemetrexed Disodium Hydrate exhibit inhibitory activities towards thymidylate synthase as well as other folate dependent enzymes.

Safety

• Symbol(GHS): GHS08
• Signal word: Danger
• Hazard statements: H360-H341
• Precautionary statements: P201-P202-P281-P308+P313-P405-P501
• target organs: Blood,Immune system,Testes
• WGK Germany: WGK 3
• Storage Class: 6.1C - Combustible acute toxic Cat.3; toxic compounds or compounds which causing chronic effects
• Hazard Classifications: Eye Irrit. 2; Muta. 2; Repr. 1A; Skin Irrit. 2; STOT RE 1