4-BiphenylsulfonylChloride , 10mMinDMSO , 1623-93-4

Synonym(s):
(4-Biphenylyl)sulfonyl chloride;p-Biphenylsulfonyl chloride;p-Phenylbenzenesulfonyl chloride;4-(Chlorosulfonyl)biphenyl;4-Phenylbenzenesulfonic acid chloride

CAS NO.：1623-93-4

Empirical Formula: C12H9ClO2S

Molecular Weight: 252.72

MDL number: MFCD00078658

EINECS: 216-609-1

PRODUCT Properties

• Melting point: 103-108 °C(lit.)
• Boiling point: 200-205°C 6mm
• Density: 1.320±0.06 g/cm3(Predicted)
• Flash point: 200-205°C/6mm
• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• solubility: DMSO: 50 mg/mL (197.85 mM)
• form: Crystalline Powder
• color: White
• Water Solubility: Reacts with water.
• Sensitive: Moisture Sensitive
• BRN: 2694373
• InChI: InChI=1S/C12H9ClO2S/c13-16(14,15)12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9H
• InChIKey: ALBQXDHCMLLQMB-UHFFFAOYSA-N
• SMILES: C1(C2=CC=CC=C2)=CC=C(S(Cl)(=O)=O)C=C1
• CAS DataBase Reference: 1623-93-4(CAS DataBase Reference)

Description and Uses

It is a reactant for preparation of anilinopyrimidinesulfonamides as potential anticancer agents, synthesis of inhibitors of the hypoxia inducible factor pathway. It participates in the preparation of hydroxy-sulfonyl-piperidinyl butyramides as HDAC inhibitors and potential antitumors and is also involved in palladium-catalyzed desulfitative C-arylation.

Safety

• Symbol(GHS): GHS05
• Signal word: Danger
• Hazard statements: H314
• Precautionary statements: P280-P305+P351+P338-P310
• Hazard Codes: C
• Risk Statements: 14-34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 3
• F: 10-21
• Hazard Note: Corrosive
• HazardClass: 8
• PackingGroup: II
• HS Code: 29049090