A6948458
Dynasore , 10mMinDMSO , 304448-55-3
Synonym(s):
3-Hydroxynaphthalene-2-carboxylic acid-(3,4-dihydroxybenzylidene)-hydrazide, Sore to Dynamin;Dynamin Inhibitor I, Dynasore - CAS 304448-55-3 - Calbiochem
CAS NO.：304448-55-3
Empirical Formula: C18H14N2O4
Molecular Weight: 322.31
MDL number: MFCD00292551
EINECS: 200-256-5
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB321.60 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | >224°C (dec.) |
| Density | 1.36±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 1 mg/ml). |
| form | Off-white solid. |
| pka | 8.49±0.35(Predicted) |
| color | Beige |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month. |
| CAS DataBase Reference | 304448-55-3 |
Description and Uses
Dynasore (304448-55-3) is a noncompetitive inhibitor of dynamin GTPase activity and blocks dynamin-dependent endocytosis in cells, including neurons. It inhibits the GTPase activity of dynamin1, dynamin2, and Drp1 (mitochondrial dynamin). It is cell permeable, fast acting (seconds) and reversible.1,2 Dynasore is a extremely useful tool for studying endocytosis and other cellular events which are dependent on dynamin.3-5
Dynamin Inhibitor I, Dynasore is an inhibitor of Dynamin I and Dynamin II.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| Hazard Codes | N |
| Risk Statements | 50 |
| Safety Statements | 22-24/25-61 |
| RIDADR | UN 3077 9/PG 3 |
| HS Code | 2928.00.2500 |
