A6955758
BAPTA-AM , 10mMinDMSO , 126150-97-8
CAS NO.：126150-97-8
Empirical Formula: C34H40N2O18
Molecular Weight: 764.68
MDL number: MFCD00036696
EINECS: 634-129-4
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB399.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 86-90°C |
| Boiling point: | 796.1±60.0 °C(Predicted) |
| Density | 1.350±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in chloroform, dimethyl sulfoxide |
| form | powder |
| pka | 1.69±0.50(Predicted) |
| color | White |
| Appearance | white to beige solid |
| λmax | 287 nm |
| BRN | 7458534 |
| Stability: | Light Sensitive |
| Biological Applications | Calcium indicators; treating cancer,chronic bacterial infection,glaucoma,ocular hypertension,HIV-associated conditions,infectious diseases,neurodegenerative disorders,neurological conditions,psychiatric conditions |
| InChIKey | YJIYWYAMZFVECX-UHFFFAOYSA-N |
| SMILES | C(OC1=CC=CC=C1N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)COC1=CC=CC=C1N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O |
| CAS DataBase Reference | 126150-97-8(CAS DataBase Reference) |
Description and Uses
BAPTA-AM (126150-97-8) is a selective cell permeable Ca2+ chelator. It is a widely used intracellular calcium sponge.1,2 Rapidly taken up by cells where it is irreversibly hydrolyzed to BAPTA by intracellular esterases. Pretreatment of cells with BAPTA-AM inhibits thapsigargin-induced responses.3
A cell permeable derivative of BAPTA which is widely used as an intracellular calcium sponge. Fluorescence: max. Abs. 287nm; e x 10-3: 5.9
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P271-P261-P280 |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| F | 8-10-21 |
| HS Code | 2921490090 |
| Storage Class | 11 - Combustible Solids |
