A6967258
CediranibMaleate , 10mMinDMSO , 857036-77-2
CAS NO.：857036-77-2
Empirical Formula: C25H27FN4O3·C4H4O4
Molecular Weight: 566.59
MDL number: MFCD27665457
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB200.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 198.3-200.08 °C (polymorph) |
| storage temp. | Store at -20°C |
| solubility | DMSO:72.5(Max Conc. mg/mL);127.96(Max Conc. mM) Water:2.0(Max Conc. mg/mL);3.53(Max Conc. mM) |
| form | Solid |
| color | White to off-white |
| InChIKey | JRMGHBVACUJCRP-BTJKTKAUSA-N |
| SMILES | C(/C(=O)O)=C/C(=O)O.O(C1=CC=C2NC(C)=CC2=C1F)C1=NC=NC2C=C(OCCCN3CCCC3)C(OC)=CC1=2 |
Description and Uses
Cediranib (AZD2171) inhibited VEGF-stimulated proliferation and KDR phosphorylation with IC50 of 0.4 and 0.5 nM, respectively.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
