Azaperone , 10mMinDMSO , 1649-18-9

Synonym(s):
1-(4-Fluorophenyl)-4-(4-(2-pyridinyl)-1-piperazinyl)-1-butanone;4′-Fluoro-4-[4-(2-pyridyl)-1-piperazinyl]butyrophenone

CAS NO.：1649-18-9

Empirical Formula: C19H22FN3O

Molecular Weight: 327.4

MDL number: MFCD00866692

EINECS: 216-715-8

PRODUCT Properties

• Melting point: 87-89?C
• Boiling point: 236°C (rough estimate)
• Density: 1.1513 (estimate)
• storage temp.: Sealed in dry,2-8°C
• solubility: DMF: 15 mg/ml; DMSO: 15 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): insol
• pka: 8.43±0.19(Predicted)
• form: Solid
• color: Light yellow to yellow
• InChI: InChI=1S/C19H22FN3O/c20-17-8-6-16(7-9-17)18(24)4-3-11-22-12-14-23(15-13-22)19-5-1-2-10-21-19/h1-2,5-10H,3-4,11-15H2
• InChIKey: XTKDAFGWCDAMPY-UHFFFAOYSA-N
• SMILES: C(C1=CC=C(F)C=C1)(=O)CCCN1CCN(C2=NC=CC=C2)CC1
• CAS DataBase Reference: 1649-18-9(CAS DataBase Reference)
• NIST Chemistry Reference: Azaperone(1649-18-9)

Description and Uses

Azaperone is a sedative used in veterinary medicine to avoid mortality of pigs during transportation. This alternative substance to chlorpromazine is a sensitizer and a photosensitizer.

H1 antihistamine (nonsedating); leucotriene synthesis blocker

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H301
• Precautionary statements: P301+P330+P331+P310
• Hazard Codes: Xn
• Risk Statements: 22
• Safety Statements: 3/14
• RIDADR: UN2811 6.1/PG 3
• WGK Germany: 3
• RTECS: EU4550000
• HS Code: 29335990
• Toxicity: dog,LDLo,oral,> 20mg/kg (20mg/kg),GASTROINTESTINAL: NAUSEA OR VOMITINGBEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE,Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 1798, 1974.